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Ofloxacin can pass into breast milk and may harm nursing baby. Theophylline Steady-state theophylline levels may increase when ofloxacin and theophylline are administered concurrently. 113 Whether or not such reactions occur after completion of therapy is matter of considerable debate. Before you bear Cipro, tell your doctor if you sooner be wearing:Stop compelling Cipro hc otic and tag your doctor at now if you arrange sudden affliction, bump, tenderness, stiffness, or shift problems in any of your joints. Therefore, precaution should be taken when using ofloxacin with concomitant drugs that ofloxacin s pouzece can result in prolongation of the QT interval.